Clinical treatment of 368 sepsis patients induced by severe surgical abdominal infection / 中华急诊医学杂志

Objective To investigate and find a multiple treatment to reduce the mortality of sepsis patients induced by severe surgical abdominal infection.Methods While treating to severe surgical abdominal infection,inflammatory mediator bacteria,extoxin and endotoxin,immunity,dysfunction of microcirculation,nutrition and metabolism and the function of organs should be paid more attention on and considered as a whole.We also carried out 14 concrete treating measurement.Combined high dosage of anisodaminum and dexamethason were used in sbort-term.Bring forward nourishment support according to different stage of MODS and applying it in clinic could significantly reduce the companion syndrome.Oral administration of“JIE-DU-GU-BEN-TANG”which developed by our division could regulate the imbalance of immunity and inflammatory mediator.Results There were 46 patients died in 368 patients,mortality was 12.50%. Conclusion It was difficult to treat sepsis patients induced by severe abdominal infection and our new multiple treatment could significantly reduce the mortality of severe sepsis.

Clinical Experience on Three-port Laparoscopic Cholecystectomy:Report of 364 Cases / 中国微创外科杂志

Objective To explore the clinical feasibility of three-port laparoscopic cholecystectomy(LC).Methods From April 2006 to April 2007,364 patients with acute or chronic cholecystitis underwent LC using three-port method.The clinical data of the patients were analyzed retrospectively.Results All of the 364 patients were cured.Three-port LC were completed in 357 of them with a success rate of 98%.Seven patients were converted to four-trocar LC because of frozen Callot's triangle and gallbladder atrophy.The operation time was 30-80 min(mean,55 min).No severe complications including bile duct injury,bile leakage,and hemorrhage,occurred in our patients.Among the patients who were treated with three-trocar LC,250 were followed up for 1 to 13 months with a mean of 5 months.During the follow-up,no bile duct stenosis,gallbladder pouch,or residual stones were found.Conclusion Three-port LC is safe,effective,and feasible for patients with cholecystitis,if the surgeons have grasped the techniques of four-port LC.